Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. ALFAM 400MG TABLET should be taken with or after food.

- Alcohol : UNSAFE

Do not drink alcohol while you are taking this medicine. ALFAM 400MG TABLET may cause excessive drowsiness when taken with alcohol. | - Pregnancy : CONSULT YOUR DOCTOR

The safety of ALFAM 400MG TABLET during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing. | - Breast feeding : SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant. | - Driving : UNSAFE

ALFAM 400MG TABLET may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur. | - Kidney : CAUTION

ALFAM 400MG TABLET should be used with caution in patients with severe kidney disease. Dose adjustment may be needed. | - Liver : UNSAFE

ALFAM 400MG TABLET is unsafe to use in patients with liver disease and should be avoided.

If you miss a dose of ALFAM 400MG TABLET, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Is it safe to use ALFAM 400MG TABLET?::: ALFAM 400MG TABLET is safe for most patients. However, in some patients, it may cause some unwanted side effects like nausea, vomiting, stomach pain, heartburn and diarrhea. Inform your doctor if you experience any persistent problem due to this medication.| What should I tell my doctor before starting treatment with ALFAM 400MG TABLET?::: Before starting treatment with ALFAM 400MG TABLET, tell your doctor if you have any other health problems, like kidney or liver-related issues. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are planning a baby, if you are pregnant or breastfeeding.| What if I forget to take a dose of ALFAM 400MG TABLET?::: If you forget a dose of ALFAM 400MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.| Can I stop taking ALFAM 400MG TABLET when my pain is relieved?::: ALFAM 400MG TABLET should be continued as advised by your doctor, if you are using the medicine for a condition associated with long-term pain. It can be discontinued if you are using it for short-term pain relief.| Can the use of ALFAM 400MG TABLET cause nausea and vomiting?::: Yes, the use of ALFAM 400MG TABLET may cause nausea and vomiting. Taking it with milk, food or antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine or a low frequency of urination. Do not take any other medicines without speaking to your doctor.| Are there any specific contraindications associated with the use of ALFAM 400MG TABLET?::: The use of ALFAM 400MG TABLET is considered to be harmful for patients with known allergy to any of the components of this medicine. It should be avoided in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active or recurrent stomach ulcer/bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, and liver or kidney disease.| Is ALFAM 400MG TABLET helpful in relieving stomach pain?::: No, ALFAM 400MG TABLET should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.| Can the use of ALFAM 400MG TABLET cause damage to kidneys?::: Yes, the long-term use of ALFAM 400MG TABLET can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect the kidneys from damage. Use of painkillers lowers the levels of prostaglandins in the body, leading to kidney damage because of long-term use. Therefore, the use of painkillers is not recommended in patients with underlying kidney disease.| Is it safe to take a higher than the recommended dose of ALFAM 400MG TABLET?::: No, taking a higher than the recommended dose of ALFAM 400MG TABLET can increase the risks of side effects like nausea, vomiting, heartburn, indigestion and diarrhea. In fact, using this medicine for a long-term can also damage your kidneys on long-term use. If you are experiencing increased severity of pain or if the pain is not relieved by the recommended doses of this medicine, please consult your doctor for re-evaluation.| Can ALFAM 400MG TABLET cause dizziness?::: Yes, ALFAM 400MG TABLET can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, do not drive or use any machines. It is better to rest for sometime and resume once you feel better.

ALFAM 400MG TABLET is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

-Methotrexate (Injection Route): Severe

Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.

| -Methotrexate (Injection Route): Severe

Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.

| -Methotrexate (Injection Route): Severe

Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.

| -Methotrexate (Injection Route): Severe

Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.

| -Pemetrexed (Injection Route): Severe

Ibuprofen may increase the effect of Pemetrexed. Ibuprofen may increase the effect of Pemetrexed.Do not take Ibuprofen days before, the day of, and 2 days following Pemetrexed.

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