Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aiitrex 25mg Tablet may be taken with or without food.

- Alcohol : UNSAFE

It is unsafe to consume alcohol with Aiitrex 25mg Tablet | - Pregnancy : UNSAFE

Aiitrex 25mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant. | - Breast feeding : UNSAFE

Aiitrex 25mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. | - Driving : CONSULT YOUR DOCTOR

It is not known whether Aiitrex 25mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor. | - Kidney : CAUTION

Aiitrex 25mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.Regular monitoring of kidney function test is advised while you are taking this medicine. | - Liver : CAUTION

Aiitrex 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

If you miss a dose of Aiitrex 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Can Aiitrex 25mg Tablet cause mouth ulcers?::: Yes, Aiitrex 25mg Tablet can cause a sore mouth and mouth ulcers as side effects in some cases. Taking folic acid along with Aiitrex 25mg Tablet may help in reducing the ulcers. Ask your doctor if the dose can be reduced, as dose reduction may further help in reducing the ulcers.| Why do I have to take folic acid with Aiitrex 25mg Tablet?::: Folic acid is required to make new cells in the body, and Aiitrex 25mg Tablet decreases the folic acid levels in the body. Folic acid can help reduce some of the side effects of Aiitrex 25mg Tablet, such as mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia, and liver problems.| Why do I need to take regular blood tests while taking Aiitrex 25mg Tablet?::: Regular blood tests will help your doctor to check your response to Aiitrex 25mg Tablet and monitor you for side effects. You will need to regularly check your liver function and your blood counts (white blood cells, red blood cells, and platelets). Your doctor may also order additional tests depending on the results.| Can Aiitrex 25mg Tablet use make me more prone to infections?::: Aiitrex 25mg Tablet may decrease the activity of your immune system. As a result, you may develop serious infections. There have been rare reports that suggest the occurrence of serious lung infections with the use of Aiitrex 25mg Tablet. If you have an active infection, Aiitrex 25mg Tablet should be used with extreme caution.| Can Aiitrex 25mg Tablet affect fertility?::: Yes, Aiitrex 25mg Tablet may affect fertility in both males and females. It may cause a decrease in sperm count in males and menstrual disturbances in females. No need to worry; these effects are reversible and disappear once the therapy is discontinued.| What to do if I am planning to become pregnant and my husband is taking Aiitrex 25mg Tablet?::: You should avoid pregnancy if your husband is taking Aiitrex 25mg Tablet. Also, it is advised that pregnancy should be further avoided for a minimum of 3 months after the therapy, as it can lead to serious fetal abnormalities.

Aiitrex 25mg Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division, and leads to anti-inflammatory actions. Aiitrex 25mg Tablet kills cancer cells by preventing them from making DNA. Aiitrex 25mg Tablet can help control psoriasis by retarding the production of skin cells and suppressing inflammation. Aiitrex 25mg Tablet may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis or damage to the intestine in Crohn's disease.

-Filgrastim (Injection Route): Severe

Do not consume Filgrastim from 24 hours before or 24 hours after taking Methotrexate. Please consult with your doctor. Methotrexate may reduce the efficacy of Filgrastim.

| -Acitretin (Oral Route): Severe

Avoid concurrent use, please consult with your doctor. Concurrent use may cause serious liver dysfunction.

| -Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route): Severe

Do not use Methotrexate with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). If essential, please consult your doctor. Methotrexate may reduce efficacy of Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).

| -Phenytoin (Oral Route): Severe

Please consult with your doctor. Doctor may monitor kidney and liver function. Concurrent use may increase the risk of serious side effects of Methotrexate.

| -Phenytoin (Injection Route): Severe

Please consult with your doctor. Doctor may monitor kidney and liver function. Concurrent use may increase the risk of serious side effects of Methotrexate.

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