Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Afinitor 5mg Tablet may be taken with or without food.

- Alcohol : CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Afinitor 5mg Tablet. Please consult your doctor. | - Pregnancy : CONSULT YOUR DOCTOR

Afinitor 5mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks. | - Breast feeding : CONSULT YOUR DOCTOR

Afinitor 5mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor. | - Driving : UNSAFE

Afinitor 5mg Tablet may cause side effects that could affect your ability to drive.As fatigue is a common side effect with Afinitor 5mg Tablet and this may affect your ability to drive | - Kidney : SAFE IF PRESCRIBED

Afinitor 5mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended. | - Liver : CAUTION

Afinitor 5mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.Use of Afinitor 5mg Tablet is not recommended in patients with severe liver disease.

If you miss a dose of Afinitor 5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\t\t

Is any monitoring required while taking Afinitor 5mg Tablet?::: Regular monitoring is required while you are on Afinitor 5mg Tablet. The doctor will advise blood tests to see the counts of red blood cells, white blood cells, and platelets since the counts may decrease during treatment with Afinitor 5mg Tablet. Also, blood tests will be required to check your kidney function, liver function, blood glucose levels, and cholesterol levels.| What should I avoid while taking Afinitor 5mg Tablet?::: You should avoid grapefruit or grapefruit juice while taking Afinitor 5mg Tablet. This is because taking them together may increase the levels of Afinitor 5mg Tablet in your blood to harmful levels. Avoid the use of live vaccinations and any possible contact with individuals who have received live vaccinations.| What is the most important information I need to know about Afinitor 5mg Tablet?::: Afinitor 5mg Tablet can cause serious side effects which include severe allergic reactions, angioedema, and kidney failure which can be severe and can lead to death. It is possible that you may develop an infection or problems related to lung such as breathing problems.| Is Afinitor 5mg Tablet a chemotherapy?::: Afinitor 5mg Tablet is an anticancer medicine. It belongs to kinase inhibitor class of medicines. It works by reducing the blood supply to the tumor, which slows down the growth and spread of cancer cells.| How is Afinitor 5mg Tablet administered?::: Usually, Afinitor 5mg Tablet is taken once or twice daily. The medicine should always either be taken with food or always be taken without food. Afinitor 5mg Tablet should be swallowed whole with water and should not be crushed or chewed.| How long can you take Afinitor 5mg Tablet?::: There is no definite duration of treatment with Afinitor 5mg Tablet. Afinitor 5mg Tablet is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.| How will I know that Afinitor 5mg Tablet is shrinking my brain tumor?::: The effect of Afinitor 5mg Tablet in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.| Is Afinitor 5mg Tablet cytotoxic?::: Yes, Afinitor 5mg Tablet is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).| Is Afinitor 5mg Tablet a chemotherapy?::: Afinitor 5mg Tablet is an anticancer medicine. It belongs to kinase inhibitor class of medicines. It works by reducing the blood supply to the tumor, which slows down the growth and spread of cancer cells.| How is Afinitor 5mg Tablet administered?::: Usually, Afinitor 5mg Tablet is taken once or twice daily. The medicine should always either be taken with food or always be taken without food. Afinitor 5mg Tablet should be swallowed whole with water and should not be crushed or chewed.| How long can you take Afinitor 5mg Tablet?::: There is no definite duration of treatment with Afinitor 5mg Tablet. Afinitor 5mg Tablet is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.| Is any monitoring required while taking Afinitor 5mg Tablet?::: Regular monitoring is required while you are on Afinitor 5mg Tablet. The doctor will advise blood tests to see the counts of red blood cells, white blood cells, and platelets since the counts may decrease during treatment with Afinitor 5mg Tablet. Also, blood tests will be required to check your kidney function, liver function, blood glucose levels, and cholesterol levels.| How will I know that Afinitor 5mg Tablet is shrinking my brain tumor?::: The effect of Afinitor 5mg Tablet in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.| What should I avoid while taking Afinitor 5mg Tablet?::: You should avoid grapefruit or grapefruit juice while taking Afinitor 5mg Tablet. This is because taking them together may increase the levels of Afinitor 5mg Tablet in your blood to harmful levels. Avoid the use of live vaccinations and any possible contact with individuals who have received live vaccinations.| What is the most important information I need to know about Afinitor 5mg Tablet?::: Afinitor 5mg Tablet can cause serious side effects which include severe allergic reactions, angioedema, and kidney failure which can be severe and can lead to death. It is possible that you may develop an infection or problems related to lung such as breathing problems.| Is Afinitor 5mg Tablet cytotoxic?::: Yes, Afinitor 5mg Tablet is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).

Afinitor 5mg Tablet suppresses the activity of body's immune system and prevents rejection of the transplanted organ.

-Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route): Life-threatening

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) should not be used while undergoing treatment with Everolimus or for up to 6 months after stopping Everolimus. Concomitant use may cause a severe drop in blood pressure that may lead to a heart attack.

| -Natalizumab (Injection Route): Life-threatening

Do not consume Natalizumab with Everolimus. Concurrent use may increase the risk of certain brain infections.

| -Cholera Vaccine (Inactivated) (Oral Route): Severe

Cholera Vaccine (Inactivated) should not be used while undergoing treatment with Everolimus or for up to 6 months after stopping Everolimus. Concomitant use may cause a severe drop in blood pressure that may lead to a heart attack.

| -Purified Vi Polysaccharide Typhoid Vaccine (Injection Route): Severe

Purified Vi Polysaccharide Typhoid Vaccine should not be used while undergoing treatment with Everolimus or for up to 6 months after stopping Everolimus. Concomitant use may cause a severe drop in blood pressure that may lead to a heart attack.

| -Temsirolimus (Injection Route): Severe

Concurrent use should be avoided. Concurrent use may increase the risk of serious swelling of the airways or tongue.

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