This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

- Alcohol : None

No interaction found/established | - Pregnancy : SAFE IF PRESCRIBED

Afdethro Cream is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies. | - Breast feeding : SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant. | - Driving : None

No interaction found/established | - Kidney : None

No interaction found/established | - Liver : None

No interaction found/established

If you miss a dose of Afdethro Cream, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

How should Afdethro Cream be applied?::: Afdethro Cream should be applied twice daily. It should be applied to a dry, clean face to lessen the possibility of irritation. Spread it gently and uniformly in a thin layer but you need not rub it in.| What is Afdethro Cream used for?::: Afdethro Cream is used for treatment of acne vulgaris also known as pimples or spots. It is used to reduce the growth of bacteria which cause acne. It can also be used to treat skin infections.| What precautions need to be followed while applying Afdethro Cream?::: Afdethro Cream should be applied cautiously. It should not come into contact with the eyes, lips, or the lining of the mouth or nose. Do not apply to broken skin. If accidental contact occurs, rinse thoroughly with water. Be careful not to use cosmetic products containing alcohol, irritant, or medicated soaps, as these may cause irritation or drying effects.| How long does it take for Afdethro Cream to work for acne?::: Successful treatment of acne may take several weeks or even months. The normal treatment time is 10 to 12 weeks. Consult your doctor, if you do not see improvement at the end of the prescribed course of treatment.| If Afdethro Cream does not help me with acne, can I use clindamycin?::: If you have already used Afdethro Cream, antibiotics of the same class (macrolides), clindamycin and lincomycin may also not work. This could be because of drug resistance. In this, the bacteria gets modified in your body and medicines may not be able to treat the new modified form.| How should Afdethro Cream be stored?::: Store it in a cool dry place below 25 degrees centigrade. Some of the preparations may contain alcohol, which are flammable, and therefore should be kept away from high temperatures.| What if I forget to apply Afdethro Cream?::: Try not to forget to use Afdethro Cream, as missing an application will slow down the healing process. However, if you have missed an application, use Afdethro Cream as soon as you remember, but a gap of about three hours is required before you use it again.

Afdethro Cream is an antibiotic which stops the growth of acne-causing bacteria on the skin. It does so by preventing synthesis of essential proteins required by these bacteria to carry out vital functions.

-Estradiol (Oral Route): Moderate

Talk to your doctor if you notice any unusual symptoms. Erythromycin may raise blood levels of Estradiol.Concurrent use may increase side effects of Estradiol.

| -Estrogen (Oral Route): Moderate

Talk to your doctor if you notice any unusual symptoms. Erythromycin may raise blood levels of Estrogen.Concurrent use may increase side effects of Estrogen.

| -Estradiol (Injection Route): Moderate

Talk to your doctor if you notice any unusual symptoms. Erythromycin may raise blood levels of Estradiol.Concurrent use may increase side effects of Estradiol.

| -Fluvastatin (Oral Route): Moderate

Talk to your doctor if you experience muscle pain, tenderness, or weakness during the simultaneous use of these medicines. Concurrent use may increase the risk of muscle damage.

| -Estradiol (Skin Route): Moderate

Talk to your doctor if you notice any unusual symptoms. Erythromycin may raise blood levels of Estradiol.Concurrent use may increase side effects of Estradiol.

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