In Treatment of Primary biliary cirrhosis Primary biliary cholangitis is a type of liver disease that gradually gets worse over time. It does not always have symptoms but, over time, it can lead to liver failure. Adebile 300 Tablet is used to treat this condition and may be used by itself or with other medicines. It can help prevent or delay liver damage in most people, especially if you start taking it in the early stages. Once you start this treatment, you will likely be taking it for the rest of your life. To make the medicine more effective and for general health benefits, you can help yourself by stopping smoking, keeping a healthy weight, and not drinking too much alcohol.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Adebile 300 Tablet is to be taken with food.
- Alcohol : CAUTION
Caution is advised when consuming alcohol with Adebile 300 Tablet. Please consult your doctor. | - Pregnancy : CONSULT YOUR DOCTOR
Adebile 300 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. | - Breast feeding : CAUTION
Adebile 300 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body. | - Driving : SAFE
Adebile 300 Tablet does not usually affect your ability to drive. | - Kidney : CONSULT YOUR DOCTOR
There is limited information available on the use of Adebile 300 Tablet in patients with kidney disease. Please consult your doctor. | - Liver : CAUTION
Adebile 300 Tablet should be used with caution in patients with liver disease. Dose adjustment of Adebile 300 Tablet may be needed. Please consult your doctor.
If you miss a dose of Adebile 300 Tablet, skip it and continue with your normal schedule. Do not double the dose.
When should I take Adebile 300 Tablet?::: The suitable timing of taking this medicine might differ depending on your condition. Your doctor might instruct you to take 2 to 3 doses per day and suggest taking the last dose at bedtime. Adebile 300 Tablet should be taken with water or milk after food. When prescribed for dissolving gallstones, it is usually suggested to be taken once daily at night.| Is Adebile 300 Tablet safe?::: Adebile 300 Tablet is usually considered to be a safe and effective medicine. However, this medicine may have some common side effects, such as diarrhea. If diarrhea occurs, your doctor may reduce the dose, and if it persists, your treatment may be discontinued. Additionally, using this medicine as a long-term therapy may also affect your liver enzyme levels. To keep a check on this, your doctor will keep monitoring your liver enzyme levels regularly. Despite these minor side effects, this medicine is supposed to be a good alternative to surgery in some patients with gallstones.| How does Adebile 300 Tablet help the liver?::: Adebile 300 Tablet acts on the liver and gets concentrated in the bile secreted from the liver. This, as a result, suppresses the synthesis and secretion of cholesterol by the liver, thereby decreasing the cholesterol levels in bile. This medicine also acts by stopping the intestines from absorbing the bile salts and cholesterol. So, the reduced cholesterol saturation in the bile from the liver leads to the gradual dissolving of cholesterol from gallstones, leading to a decrease in size and their eventual dissolution. It also reduces elevated liver enzyme levels by increasing the bile flow through the liver, hence protecting the liver cells.| Does Adebile 300 Tablet cause weight gain?::: Yes, there is a chance of weight gain with Adebile 300 Tablet, but it is not common. The use of Adebile 300 Tablet can cause weight gain when prescribed in patients with liver disease associated with chronic stasis of bile in the small bile ducts of the liver. In such conditions, bile cannot flow from the liver to the small intestine. Again, the chance of weight gain varies from person to person depending on the disease, so consult your doctor if you experience weight gain.| What should I avoid while taking Adebile 300 Tablet?::: While taking Adebile 300 Tablet, avoid taking an antacid preparation without consulting your doctor, as they decrease the effectiveness of Adebile 300 Tablet. You should also avoid medicines like cholestyramine or colestipol, as they affect the effectiveness of Adebile 300 Tablet. Ask your doctor about the time gap that should be maintained between Adebile 300 Tablet and these medicines. Also, avoid taking oral contraceptives, estrogenic hormones, and blood cholesterol-lowering agents such as clofibrate, as they may increase the chances of developing gallstones and act opposite to the Adebile 300 Tablet.
Adebile 300 Tablet is a hepatoprotective medication. It works by reducing the amount of cholesterol in the blood and helps dissolve gallbladder stones that are composed mainly of cholesterol. It also improves liver enzymes, protects liver cells from injury caused due to toxic bile acids, and improves liver function.
-Magaldrate (Oral Route): Moderate
Ensure a gap of at least 2 hours between taking Ursodeoxycholic Acid and Magaldrate. Magaldrate may decrease the absorption of Ursodeoxycholic Acid.
| -Allylestrenol (Oral Route): Moderate
Careful consideration is advised when taking Ursodeoxycholic Acid with Allylestrenol. Your doctor may monitor your treatment and adjust the doses as per the observations. Concurrent use may promote gallstone formation.
| -Bezafibrate (Oral Route): Moderate
Do not consume Ursodeoxycholic Acid with Bezafibrate. If concurrent use is essential, your doctor may monitor the effects of Ursodeoxycholic Acid along with your overall treatment and adjust the doses as per the observations. Bezafibrate may reduce the efficacy of Ursodeoxycholic Acid.
| -Cholestyramine (Oral Route): Moderate
Ensure a gap of at least 2 hours between taking Ursodeoxycholic Acid and Cholestyramine. Your doctor may monitor the effects of Ursodeoxycholic Acid. Cholestyramine may reduce blood levels of Ursodeoxycholic Acid.
| -Colesevelam (Oral Route): Moderate
Ensure a gap of at least 4 hours between taking Ursodeoxycholic Acid and Colesevelam. Your doctor may monitor your treatment and adjust the doses as per the observations. Colesevelam may reduce blood levels of Ursodeoxycholic Acid.