Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Adcapone Tablet may be taken with or without food.

- Alcohol : CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Adcapone Tablet. Please consult your doctor. | - Pregnancy : CONSULT YOUR DOCTOR

The safety of Adcapone Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing. | - Breast feeding : CAUTION

Adcapone Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body. | - Driving : UNSAFE

Adcapone Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur. | - Kidney : CAUTION

Adcapone Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed. | - Liver : UNSAFE

Adcapone Tablet is unsafe to use in patients with liver disease and should be avoided.

If you miss a dose of Adcapone Tablet, skip it and continue with your normal schedule. Do not double the dose.

Can Adcapone Tablet be crushed or split? If not, then how it should be taken?::: No, Adcapone Tablet should not be crushed or split. Take it as a whole with a full glass of water at the same time as you take a dose of levodopa| Does Adcapone Tablet have any effect on urine color?::: Yes, Adcapone Tablet may cause your urine to change to a brownish-orange color. This effect is common and is not harmful.| Will Adcapone Tablet make me sleepy?::: The combined use of Adcapone Tablet and levodopa has been associated with cases of excessive daytime sleepiness and sudden sleep onset episodes. If you experience these symptoms, then you should neither drive nor operate other complex machinery. Consult your doctor if it becomes troublesome.| What is meant by impulse control disorder caused by Adcapone Tablet?::: In impulse control disorders, you may get urges or cravings to behave in ways that are unusual for you. In such disorders, you cannot resist the impulse, drive or temptation to carry out certain activities that could harm yourself or others. Additionally, it may include addictive gambling, excessive eating or spending, an abnormally high sex drive or a preoccupation with an increase in sexual thoughts or feelings. In such a case, your doctor may suggest dose reduction or discontinuation of dose.| What if I accidentally take more than the recommended doses of Adcapone Tablet?::: In case you take more than the recommended doses of Adcapone Tablet, you may experience confusion, decreased activity, sleepiness, decreased muscle tone, skin discoloration, and urticaria. If any such symptoms occur, you should seek immediate medical attention in a nearby hospital or contact your doctor.| Does Adcapone Tablet cross the blood-brain barrier?::: No, Adcapone Tablet does not cross the blood-brain barrier. It is useful in prolonging the duration of the benefit obtained from individual doses of levodopa.| Does Adcapone Tablet affect fertility?::: No, Adcapone Tablet does not affect fertility. However, it should be avoided by pregnant and lactating women because there is no sufficient data to support the safety of this patient group.| Is Adcapone Tablet a dopamine agonist?::: No, it is not a dopamine agonist. Adcapone Tablet is a selective and reversible inhibitor of COMT (catechol-O-methyltransferase) which works by increasing and maintaining sustained levels of levodopa when levodopa is given along with it.

Adcapone Tablet is a selective reversible inhibitor that is given in combination with levodopa. It works by inhibiting a chemical messenger [catechol-O-methyl transferase (COMT)] which in turn helps in increasing the amount of dopamine (chemical messenger) in the brain. Thus, an adequate amount of dopamine in the brain helps to coordinate body movements.

-Adrenaline (Injection Route): Moderate

Your doctor may monitor the effects of Adrenaline when taken concurrently with Entacapone. Concurrent use may cause disturbances in heart rhythm.

| -Apomorphine (Sublingual route): Moderate

If concurrent use is essential, your doctor may monitor Apomorphine levels along with your overall treatment and adjust the doses as per the observations. Entacapone may raise blood levels of Apomorphine.

| -Apomorphine (Injection Route): Moderate

If concurrent use is essential, your doctor may monitor Apomorphine levels along with your overall treatment and adjust the doses as per the observations. Entacapone may raise blood levels of Apomorphine.

| -Dobutamine (Injection Route): Moderate

Your doctor may monitor your treatment and adjust the doses as per the observations. Concurrent use may cause disturbances in heart rhythm.

| -Dopamine (Injection Route): Moderate

Your doctor may monitor your treatment and adjust the doses as per the observations. Concurrent use may cause disturbances in heart rhythm.

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