Your doctor or nurse will give you this medicine. Kindly do not self administer.

- Alcohol : CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Actilyse 50mg Injection. Please consult your doctor. | - Pregnancy : CONSULT YOUR DOCTOR

The safety of Actilyse 50mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing. | - Breast feeding : SAFE IF PRESCRIBED

Actilyse 50mg Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. | - Driving : NOT RELEVANT

Not relevant, as Actilyse 50mg Injection is intended for use in hospitalized patients. | - Kidney : SAFE IF PRESCRIBED

Actilyse 50mg Injection is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed. | - Liver : CONSULT YOUR DOCTOR

There is limited data available on the use of Actilyse 50mg Injection in patients with liver disease.

If you miss a dose of Actilyse 50mg Injection, please consult your doctor.

How is Actilyse 50mg Injection administered?::: Actilyse 50mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor?s instructions carefully to get maximum benefit from Actilyse 50mg Injection.| Is Actilyse 50mg Injection safe?::: Actilyse 50mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.| Can the use of Actilyse 50mg Injection increase the risk of bleeding?::: Yes, Actilyse 50mg Injection can increase the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.| What medicines should I avoid while taking Actilyse 50mg Injection?::: Actilyse 50mg Injection can interact with several medicines. If you are already taking Actilyse 50mg Injection, do not take any other medicine without talking to your doctor.| When will I feel better after taking Actilyse 50mg Injection?::: Actilyse 50mg Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Actilyse 50mg Injection. This does not mean that the medicine is not working, therefore keep taking this medicine as prescribed.

Actilyse 50mg Injection is a thrombolytic medication. It works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes.

-Apixaban (Oral Route): Severe

Do not consume Apixaban with Alteplase. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Alteplase may increase the effect of Apixaban.Concurrent use may increase the risk of bleeding.

| -Ticagrelor (Oral Route): Moderate

Talk to your doctor if you notice any unusual symptoms. Concurrent use may increase the risk of bleeding.

| -Rivaroxaban (Oral Route): Moderate

Talk to your doctor if you notice any unusual symptoms. Concurrent use may increase the risk of bleeding.

| -Tranexamic Acid (Oral Route): Moderate

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Tranexamic Acid may block the action of Alteplase.

| -Tirofiban (Injection Route): Moderate

Do not consume Tirofiban with Alteplase. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Concurrent use may increase the risk of bleeding.

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