Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Actiful Tablet may be taken with or without food.

- Alcohol : CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Actiful Tablet. Please consult your doctor. | - Pregnancy : CONSULT YOUR DOCTOR

The safety of Actiful Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing. | - Breast feeding : CONSULT YOUR DOCTOR

Information regarding the use of Actiful Tablet during breastfeeding is not available. Please consult your doctor. | - Driving : CAUTION

Actiful Tablet may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur. | - Kidney : CAUTION

Actiful Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed. | - Liver : CONSULT YOUR DOCTOR

There is limited data available on the use of Actiful Tablet in patients with liver disease.

If you miss a dose of Actiful Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Does Actiful Tablet raise blood pressure?::: Yes, Actiful Tablet may cause high blood pressure when you are lying flat on your back (supine hypertension). This medicine should only be used by people whose low blood pressure affects their day-to-day lives and in people who cannot be treated successfully with other therapies.| Does Actiful Tablet affect heart rate?::: Actiful Tablet may slow down the heart rate slightly. It should be used cautiously when used with other medicines (beta blockers, digitalis, etc.), which can further slow down the heart rate. Patients should be monitored if they experience symptoms that are suggestive of a slow heart rate.| Why can't I lie down after taking Actiful Tablet?::: You should not lie down immediately after taking Actiful Tablet because of the risk of supine hypertension (high blood pressure, which occurs when you are lying flat on your back). Therefore, it is recommended to take the last daily dose at least 4 hours before bedtime. To lower the chance of high blood pressure while lying down at night, try keeping your head raised.| Does Actiful Tablet work immediately?::: Actiful Tablet takes about 1 hour to show its effects. However, the action lasts for a short time only, the effect persists for about 2-3 hours.| How do I take Actiful Tablet?::: Actiful Tablet should be taken exactly as directed by your doctor. Actiful Tablet is taken orally with or without food. Swallow Actiful Tablet as a whole with a glass of water. Usually, it is advised to take the medicine three times a day [morning, midday, and late afternoon (before 6 pm)] with a gap of at least 3 hours. Take the last daily dose of Actiful Tablet before an evening meal and at least 4 hours before bedtime.| Who should not take Actiful Tablet?::: Actiful Tablet is not advised for patients having an allergy to any component of the product, severe heart disease, unusually slow heart rate, high blood pressure, or conditions causing tightening of the arteries. Along with that, treatment with Actiful Tablet should be avoided if the patient has an enlarged prostate gland, urinary retention (when the bladder can?t empty properly), pheochromocytoma (tumor of the adrenal medulla), acute or severe kidney disease, overactive thyroid, poor vision as a result of diabetes, and narrow-angle glaucoma (elevated pressure in the eye).| Is any monitoring required during Actiful Tablet treatment?::: You may need to check your blood pressure and get your kidney and liver function tests done before you start taking Actiful Tablet. Once you begin the treatment, keep a constant track of your blood pressure and heart rate, especially after lying down.| How will I know that I have developed supine hypertension?::: Symptoms of supine hypertension include chest pain, palpitations, shortness of breath, headache, and blurred vision. If you develop these symptoms, tell your doctor immediately. The doctor may reduce the dose of Actiful Tablet or may discontinue treatment if the symptoms persist.| Can I take metoprolol with Actiful Tablet?::: Using Actiful Tablet and metoprolol together can make your heart rate considerably slow. Hence, you need to be careful while using both together. If you experience slow pulse, dizziness, and fainting, inform your doctor as the dose of these medicines may need to be modified.

Actiful Tablet is an alpha-adrenergic agonist. It works by activating specific receptors on blood vessels. This causes the blood vessels to tighten, which increases blood pressure.

-Risperidone (Oral Route): Moderate

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your liver function. Midodrine may raise blood levels of the active form of Risperidone.

| -Selegiline (Oral Route): Moderate

Do not consume Selegiline with Midodrine. If concurrent use is essential, your doctor may monitor your blood pressure frequently. Concurrent use may increase the risk of a dangerous spike in blood pressure.

| -Rasagiline (Oral Route): Moderate

If concurrent use is essential, your doctor may monitor your blood pressure frequently. Concurrent use may increase the risk of a dangerous spike in blood pressure.

| -Risperidone (Injection Route): Moderate

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your liver function. Midodrine may raise blood levels of the active form of Risperidone.

| -Safinamide (Oral Route): Moderate

If concurrent use is essential, your doctor may monitor your blood pressure frequently. Concurrent use may increase the risk of a dangerous spike in blood pressure.

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